特征
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優點
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轉速可調5-80RPM,每次1RPM
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予以小鼠舒適的活動環境
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勻速,加速,多次加速模式(新)
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可用于研究運動學習機運動功能
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可使用USB閃存盤
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無需連接電腦即可儲存數據
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新版軟件
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新款觸摸屏能夠設置實驗參數、管理實驗數據。
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數據讀取:
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液晶顯示
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數據采集:
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52050-07 軟件
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轉棒開始:
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START (藍色) 鍵
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電源:
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universal input 85-264 VAC, 50-60Hz, *大40 W
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轉棒停止:
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RESET/STOP(紅色) 鍵
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工作溫度:
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10° - 40° C
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設置速度:
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功能鍵
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聲級:
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< 60 dB
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速度重置:
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RESET/STOP (紅色) 鍵
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打印:
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7145微型熱敏打印機(需購置)
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轉子:
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直徑3cm轉鼓
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|
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物理尺寸
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凈重:
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11.0 Kg
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尺寸:
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46 (w) x 28 (d) x 33 (h) cm
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毛重:
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Kg 16.0 (approx.)
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包裝尺寸:
轉子
走道寬度
下落高度
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66 x 50 x 63 cm
直徑3cm
5.7cm
16cm
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47650 小鼠轉棒儀,包括:
47650 - 320 不銹鋼感應槽
47650 - 302 說明書(在USB閃存盤內)
47650 - 010 專用軟件包(在USB閃存盤內)
USB電源和電源線
可選:
如果您需要大、小鼠兩種模型,您可以選擇以下組合裝:
47850組合裝,包含一臺小鼠轉棒儀和一臺大鼠轉棒儀。
方法文獻
§ N.W. Dunham & T.S. Miya: “A Note on a Sinple Apparatus for Detecting Neurological Deficit in Rats & Mice“ J. Am. Pharmaceut. Assoc., Scientific Edit., XLVI: No. 3, 1957
§ B.J. Jones & D.J. Roberts: “The Quantitative Measurement of Motor Inco-ordination in Naive Mice Using an Accelerating Rotarod“ J. Pharm. Pharmac.: 20: 302-304, 1968
使用轉棒儀技術的相關文獻:
§ B.J. Turner et alia: “Overexpression of Survival Motor Neuron Improves Neuromuscular Function and Motor Neuron Survival in Mutant SOD1 Mice” Neurobiol. Of Aging 35 (4): 906-915,2014
§ M. Milanese et alia: “Knocking Down Metabotropic Glutamate Receptor 1 Improves Survival And Disease Progression in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis” Neurobiology of Disease 64: 48-59, 2014
§ J.E. Lorenz: “Oxidant-Induced Activation of cGMP-Dependent Protein Kinase Iα Mediates Neuropathic Pain After Peripheral Nerve Injury” Antioxidants & Redox Signaling Jan. 2014
§ J.N. Justice et alia: “Battery of Behavioral Tests in Mice that Models Age-Associated Changes in Human Motor Function” Age Oct 2013
§ A.S. Hamlin et alia: “Lesions of the Basal Forebrain Cholinergic System in Mice Disrupt Idiothetic Navigation” PLoS ONE 8(1): e53472, 2013
§ T. Rantam?ki et alia: “The Impact of Bdnf Gene Deficiency to the Memory Impairment and Brain Pathology of APPswe/PS1dE9 Mouse Model of Alzheimer’s Disease” PLoS ONE 8(7): e68722, 2013
§ T. Murakami et alia: “Vascular Endothelial Growth Factor Electro-Gene Therapy Improves Functional Outcome in a Mouse Model of ALS” Immunology, Endocrine & Metabolic Agents: 13 (2): 107-111, 2013
§ R. Günther et alia: “Clinical Testing and Spinal Cord Removal in a Mouse Model for Amyotrophic Lateral Sclerosis (ALS)” JoVE J. Vis. Exp. (61), e3936, doi:10.3791/3936, 2012http://www.jove.com/video/3936/clinical-testing-spinal-cord-removal-mouse-model-for-amyotrophic
§ A.J. Grottick et alia: “Studies to investigate the role of 5-HT 2C Receptors on Cocaine- and Food-Maintained Behavior”: J. Pharmacol. Exper. Therap., 2000
§ L.T. Huang et alia: “Pentylenetetrazol-Induced Recurrent Seizures in Rat Pups: Time Course on Spatial Learning and Long…”: Epilepsia, 2002
§ E. Candelario-Jalil et alia: “Wide Therapeutic Time Window for Nimesulide Neuroprotection in a Model of Transient Focal Cerebral Ischemia in the Rat”: Brain Research: 177: 98-108, 2004
§ C.D. Heldermon et alia: “CliTherapeutic Efficacy of Bone Marrow Transplant, Intracranial AAV-mediated Gene Therapy, or Both in the Mouse Model of MPS IIIB” Molecular Therapy 15(5): 873-880, 2010 (rocking)
§ C.D. Heldermon et alia: “Development of Sensory, Motor and Behavioral Deficits in the Murine Model of Sanfilippo Syndrome Type B”: PLoS ONE: 8 (e772): 2007 (rocking)
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動物行為儀器:
自身給藥、條件恐懼、斯金納、震驚反射(PPI)、跑步機、各類經典迷宮等
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動物主動步態分析、動物被動步態分析、動物自由步態分析(內測中)
睡眠剝奪儀、體溫維持儀、智能熱板儀、轉棒疲勞儀、鼠尾光照測痛儀等
神經電生理:
光遺傳、無線光遺傳
光纖記錄系統(單通道、多通道)
電生理信號采集系統(腦電、肌電等)
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